{"id":5679,"date":"2025-11-13T14:19:11","date_gmt":"2025-11-13T13:19:11","guid":{"rendered":"https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/?p=5679"},"modified":"2026-01-13T14:24:50","modified_gmt":"2026-01-13T13:24:50","slug":"article-publie-sur-le-controle-qualite-des-organoides-cerebraux","status":"publish","type":"post","link":"https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/2025\/11\/13\/article-publie-sur-le-controle-qualite-des-organoides-cerebraux\/","title":{"rendered":"Article publi\u00e9 sur le contr\u00f4le qualit\u00e9 des organo\u00efdes c\u00e9r\u00e9braux"},"content":{"rendered":"<p data-start=\"391\" data-end=\"522\">Nous avons le plaisir d\u2019annoncer la publication de leur article dans <strong data-start=\"460\" data-end=\"501\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Scientific Reports<\/span><\/span><\/strong> (Nature Portfolio) :<\/p>\n<blockquote>\n<p data-start=\"524\" data-end=\"636\"><strong data-start=\"524\" data-end=\"599\">\u00ab Towards a quality control framework for cerebral cortical organoids \u00bb<\/strong><br data-start=\"599\" data-end=\"602\" \/>Castiglione, H., Madrange, L., Baquerre, C., Maisonneuve, B. G. C., Lemonnier, T., Deslys, J.-P., Yates, F., Honegger, T., Rontard, J., &amp; Vigneron, P.-A. (2025). . <i>Scientific Reports<\/i>, <i>15<\/i>(1), 29431. <a href=\"https:\/\/doi.org\/10.1038\/s41598-025-14425-x\">https:\/\/doi.org\/10.1038\/s41598-025-14425-x<\/a><br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-5681 aligncenter\" src=\"https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/wp-content\/uploads\/2025\/11\/hel1-300x265.png\" alt=\"\" width=\"300\" height=\"265\" srcset=\"https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/wp-content\/uploads\/2025\/11\/hel1-300x265.png 300w, https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/wp-content\/uploads\/2025\/11\/hel1-768x678.png 768w, https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/wp-content\/uploads\/2025\/11\/hel1.png 952w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<\/blockquote>\n<p data-start=\"524\" data-end=\"636\">Ce travail est le fruit des recherches men\u00e9es par <strong data-start=\"83\" data-end=\"124\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">H\u00e9lo\u00efse Castiglione<\/span><\/span><\/strong>, doctorante CIFRE au sein de l\u2019\u00e9quipe CellTechs, et de son encadrant de th\u00e8se <strong data-start=\"203\" data-end=\"244\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Pierre-Antoine Vigneron<\/span><\/span><\/strong> (CellTechs). Il s\u2019inscrit dans une <strong data-start=\"280\" data-end=\"348\">collaboration \u00e9troite avec <span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">NETRI<\/span><\/span><\/strong>, soci\u00e9t\u00e9 sp\u00e9cialis\u00e9e dans la microfluidique bas\u00e9e \u00e0 Lyon.<\/p>\n<p data-start=\"638\" data-end=\"909\">Cet article r\u00e9pond \u00e0 l\u2019un des d\u00e9fis majeurs du domaine des organo\u00efdes c\u00e9r\u00e9braux : garantir la <strong data-start=\"732\" data-end=\"768\">reproductibilit\u00e9 et la fiabilit\u00e9<\/strong> des mod\u00e8les gr\u00e2ce \u00e0 un cadre structur\u00e9 et standardis\u00e9 de <strong data-start=\"826\" data-end=\"868\">contr\u00f4le qualit\u00e9 (Quality Control, QC)<\/strong> pour les organo\u00efdes corticaux c\u00e9r\u00e9braux.<\/p>\n<h3 data-start=\"911\" data-end=\"964\">Vers une standardisation des organo\u00efdes c\u00e9r\u00e9braux<\/h3>\n<p data-start=\"966\" data-end=\"1348\">Les organo\u00efdes c\u00e9r\u00e9braux constituent aujourd\u2019hui des mod\u00e8les de r\u00e9f\u00e9rence en neurosciences, offrant des perspectives uniques pour l\u2019\u00e9tude du d\u00e9veloppement c\u00e9r\u00e9bral humain, des maladies neurologiques et de la neurotoxicologie. Toutefois, l\u2019absence de standards harmonis\u00e9s de contr\u00f4le qualit\u00e9 limite encore leur d\u00e9ploiement \u00e0 grande \u00e9chelle, en recherche comme en contexte industriel.<\/p>\n<p data-start=\"1350\" data-end=\"1552\">Dans cette publication, NETRI et ses partenaires proposent un <strong data-start=\"1412\" data-end=\"1449\">cadre complet de contr\u00f4le qualit\u00e9<\/strong> visant \u00e0 renforcer la robustesse, la comparabilit\u00e9 et la fiabilit\u00e9 des organo\u00efdes corticaux c\u00e9r\u00e9braux.<\/p>\n<h3 data-start=\"1554\" data-end=\"1593\">Un travail collaboratif structurant<\/h3>\n<p data-start=\"1595\" data-end=\"1891\">Cette \u00e9tude est le r\u00e9sultat d\u2019un partenariat scientifique fort entre <strong data-start=\"1664\" data-end=\"1705\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">SupBiotech<\/span><\/span><\/strong>, le <strong data-start=\"1710\" data-end=\"1751\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">CEA<\/span><\/span><\/strong> et NETRI, illustrant l\u2019importance des collaborations acad\u00e9miques\u2013industrielles pour structurer et faire progresser le champ des organo\u00efdes.<\/p>\n<p data-start=\"1893\" data-end=\"2015\"><strong data-start=\"1893\" data-end=\"1906\">R\u00e9f\u00e9rence<\/strong><br data-start=\"1906\" data-end=\"1909\" \/>Towards a quality control framework for cerebral cortical organoids. <a href=\"https:\/\/www.nature.com\/articles\/s41598-025-14425-x\">Scientific Reports<\/a> | (2025) 15:29431<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nous avons le plaisir d\u2019annoncer la publication de leur article dans Scientific Reports (Nature Portfolio) : \u00ab Towards a quality control framework for cerebral cortical organoids \u00bbCastiglione, H., Madrange, L., Baquerre, C., Maisonneuve, B. G. C., Lemonnier, T., Deslys, J.-P., Yates, F., Honegger, T., Rontard, J., &amp; Vigneron, P.-A. (2025). . Scientific Reports, 15(1), 29431. [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":5681,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[237],"tags":[],"class_list":["post-5679","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-celltechs-fr"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Article publi\u00e9 sur le contr\u00f4le qualit\u00e9 des organo\u00efdes c\u00e9r\u00e9braux - La recherche \u00e0 SupBiotech<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.supbiotech.fr\/recherche-innovation-biotechnologie\/2025\/11\/13\/article-publie-sur-le-controle-qualite-des-organoides-cerebraux\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Article publi\u00e9 sur le contr\u00f4le qualit\u00e9 des organo\u00efdes c\u00e9r\u00e9braux\" \/>\n<meta property=\"og:description\" content=\"Nous avons le plaisir d\u2019annoncer la publication de leur article dans Scientific Reports (Nature Portfolio) : \u00ab Towards a quality control framework for cerebral cortical organoids \u00bbCastiglione, H., Madrange, L., Baquerre, C., Maisonneuve, B. G. C., Lemonnier, T., Deslys, J.-P., Yates, F., Honegger, T., Rontard, J., &amp; Vigneron, P.-A. (2025). . Scientific Reports, 15(1), 29431. 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