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Bioinformatics Research Laboratory (BIRL)

Bioinformatics Research Laboratory (BIRL)

The Sup’Biotech BIRL develops in silico (i.e., computer-based) tools that apply computational chemistry, molecular modeling, and theoretical systems biology to simulate molecular and cellular processes.

BIRL Activities

Discovering modulators of cellular growth and metabolism

The BIRL’s primary goal is to identify modulators of cellular growth and metabolism. Means of inhibiting or increasing the growth of highly proliferative cells have many applications, from bioproduction to therapeutic research aimed at fighting cancer and parasitic diseases. The creation of qualitative and quantitative models of metabolism furthers therapeutic research into the mechanisms of action behind certain anticancer treatments and leads to the discovery of ways to enhance the production of secondary metabolites with high added value, like biofuels.

Developing in silico tools

BIRL research relies on

  • the use of existing bioinformatic tools employed by the pharmaceutical industry
  • the production of new computer tools or models of biological processes (i.e., metabolism) to meet research needs
  • expertise in mathematics and statistics, a central pillar of the research strategy

The aim in developing these in silico platforms is to have industrial expertise inform the development of high-tech tools for academic research, and vice versa. In concrete terms, our work leads to the discovery of new medicines (e.g., antimalarials and anticancer drugs) and the development of organisms that can be used in the most promising fields of application for biotechnology (e.g., fermentation and biofuels). 
Each year, several Sup’Biotech student interns participate in BIRL projects. This contributes valuably to their education and also benefits the laboratory, which is eager to welcome students interested in bioinformatics.

Dr. Jean-Yves TROSSET

Dr. Alexandre ISMAIL

Dr. Ouerdia ARKOUN

About Sup’Biotech

Sup’Biotech is a school specialized in Biotechnology which provide an
innovative course taught over 5 years after the highschool Degree.
The school is close to both the world of scientific research as well as the
corporate world ans has signed partnerships with universities globally.
Graduates gain quick access to senior position both in France and
abroad in such fields as health and pharmaceuticals, food-processing
innovation, cosmetics, bioinformatics or the environment.
The studies, combining academic fundamentals, student projects and
internships are divided into two parts according to European standards:
the preparatory cycle (2 years) and the engineering cycle (3 years).
Sup’Biotech’s Biotechnology engineering program is accredited by
Medicen Paris Région and Industries and Agro-Resources (I.A.R.).
Sup’Biotech also offers an apprenticeship program starting at the
baccalaureate level, as well as a Bachelor’s degree in Biotechnology,
which is accessible after highschool Degree.


Privately Endowed Graduate Educational Institution - Education Authority of Créteil Registration - This school is a member of IONIS Education Group such as :