CellTechs Research Laboratory

The work of the CellTechs laboratory helps expand our understanding of neurodegenerative illnesses like Alzheimer’s, Parkinson’s, and Creutzfeldt-Jakob disease, and find therapeutic solutions for them.

Cellular Engineering Laboratory

Cellular Reprogramming

In 2007, in Japan, Prof. S. Yamanaka developed the technique of cellular reprogramming, a major breakthrough. Cellular reprogramming now allows us to obtain an unlimited number of stem cells starting with just a few skin cells. These induced pluripotent stem cells, or iPS cells, are potentially immortal. Not only can they proliferate indefinitely, they are a nearly inexhaustible source of human tissue. One of the most modern, innovative applications of cell biology, cellular reprogramming offers the hope of an unlimited supply of many types of human cells (e.g., retinal, neuronal, cardiac…).

Enhancing Our Understanding of Neurodegenerative Diseases

The goal of our research laboratory is to use iPS cells to better understand the mechanisms underlying neurodegenerative illnesses like Alzheimer’s, Parkinson’s, and Creutzfeldt-Jakob disease, so that we may develop therapeutic solutions to counter them. To meet this objective, our laboratory has devised a technique to prepare human “minibrains” (cerebral organoids) that may allow us to study more finely the pathological mechanisms of neurodegenerative diseases and test new treatments.
In association with techniques of genetic engineering that include the use of lentiviruses and CRISPR/Cas9, this technology paves the way for the development of new models for the treatment of these diseases.

Each year our laboratory hosts Sup’Biotech interns, allowing them to learn from the technologies developed by our teams while benefiting from their energy and inventive spirit.

Dr. Frank YATES

Dr. Rafika JARRAY

Dr. Ferid NASSOR

Dr. Vanessa PERDIZ

Dr. Elise DELAGE


Mary-Amélie MASSON

About Sup’Biotech

Sup’Biotech is a school specialized in Biotechnology located in the south of Paris, France. We provide an innovative course taught over five years after the high school diploma. The school is close to both the world of scientific research as well as the corporate world and has signed partnerships with universties globally. Graduates gain quick access to senior positions both in France and abroad in such fields as health and pharmaceuticals, food-processing innovation, cosmetics, bioinformatics, or the environment. The program is constructed around the model put in place by the international LMD reform: the Bachelor of Biotechnology cycle (3 years) and the Expertise cycle (2 years).

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